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Mitul Mehta

Professor Mitul Mehta

Director, Centre for Innovative Therapeutics

  • Professor of Neuroimaging & Psychopharmacology

Contact details

Biography

Mitul Mehta is Professor of Neuroimaging & Psychopharmacology at the Institute of Psychiatry, Psychology & Neuroscience at King's College London.

Mitul joined King’s College London as a post-doctoral researcher in Neuroimaging in 2003 with the aim of setting up a research group focussed on pharmacological neuroimaging using MRI methodology.

He worked with positron emission tomography at Imperial College for a number of years as an MRC Training Fellow before moving to King’s; a Wellcome Trust Value in People Award enabled the transition. His work was recognised by the British Association for Psychopharmacology Young Investigator Award.

At King’s his group brought quantitative methods to identify drug mechanisms and classify different compounds and used classic tracking methods to develop assays of drug modulation. These methods are utilised to understand existing compounds as well as assay novel compounds and we have tested various mechanisms, including in collaboration with the pharmaceutical industry.

Currently, Mitul is Head of the Neuropharmacology Group and Section in the Department of Neuroimaging, Theme Lead of Experimental Medicine and Novel Therapeutics at the NIHR Biomedical Research Centre: Maudsley for Mental Health and Director of the Centre for Innovative Therapeutics.

Outside of King’s, he has served on the Council for the British Association for Psychopharmacology as a member (2011-2014) and meetings secretary (2015-2020).

Research interests

Mitul has a keen interest in brain modulation methods, primarily with pharmacological agents with a goal to enhance research into novel treatment in psychiatric and neurological syndromes. He works on all stages of the research process in humans, including practical aspects of study design and implementation, novel task development, image acquisition and analytical approaches.

He has examined drugs that target dopamine, noradrenaline, serotonin, glutamate, acetycholine and histamine receptors as well as intracellular modulators. Our work is relevant for multiple syndromes including ADHD, schizophrenia, depression and Parkinson’s disease.

Teaching

  • Research Methods
  • Pharmacological Imaging

Expertise and public engagement

Mitul has been involved with the British Association for Psychopharmacology in organising the annual Summer Meeting, including a lecture for the public. He also co-leads a biennial residential course in non-clinical psychopharmacology.

He have acted as a consultant to various companies and sat on advisory boards.

In terms of public engagement, he and group members regularly work with the scientific or general media on articles, interviews, programming. They had a live experiment to showcase psychopharmacology research at the Science Gallery.

    Research

    London landscape
    Ageing Research at King's (ARK)

    Cross faculty consortium addressing ageing and healthy longevity.

    pexels-anna-shvets-4226219-min
    ATTENS Project

    The ATTENS Project explores the potential of eTNS in improving symptoms, cognitive performance and the functioning of the brain in children with ADHD.

    Project status: Completed

    ebrain-cropped-780x440
    e-BRAIN

    e-BRAIN: The impact of early adversity on trajectories of brain maturation and mental health in young adolescents

    Project status: Ongoing

    MRI Scanner
    Identifying Neuroimaging Biomarkers of Bipolar Depression

    This study aims to identify brain scanning biomarkers which can be used to help diagnose and treat patients and the development of new medications.

    Project status: Completed

    Centre for Neuroimaging
    Ketamine Research

    Using brain imaging techniques, we will observe the effects of ketamine treatment on brain activity patterns and how this relates to any changes in the symptoms of treatment resistant depression.

    King’s Open Research Group Initiative (KORGI)

    The King’s Open Research Group Initiative (or KORGI) is an action-oriented committee composed of an interdisciplinary mix of senior academics and experienced research staff that seek to change policy and procedures to promote transparent, accessible and reproducible research.

    thumbnaillogogvs2
    Centre for Innovative Therapeutics (C-FIT)

    C-FIT accelerates research with the aim of transforming lives.

    CFIT_KCL_Thumbnails_LogoStacked_4_780_440ppi
    Point-of-care testing

    Point of care testing for clozapine levels in patient blood.

    Project status: Completed

    spilled-medication
    kEtamine for the treatment of DEpression with anorexia Nervosa (EDEN)

    The EDEN trial aims to investigate the effect of ketamine in alleviating depression with a diagnosis of persisting anorexia and treatment-resistant depression

    Project status: Ongoing

    News

    King's plays major role in £50 million government funded programme into mental health research

    Researchers at King's, University of Oxford and Cardiff University will help transform mental health data, clinical trials and industry partnerships as part...

    IoPPN signage

    Warm and consistent parenting can lead to meaningful changes in brain function and learning style in children with behaviour problems

    Parenting programmes can lead to changes in how children with conduct problems process rewards in their brains.

    Young children playing with adults

    Researchers receive £4.1million to research new modelling and treatment approaches for auditory hallucinations in people with psychosis

    The Wellcome Trust Mental Health Award will fund testing of a computational model of the role of cortical circuits in understanding auditory hallucinations...

    Abstract image of a brain from above

    £1.4 million awarded to study how brain experiences paranoia

    The project "Bridging the Neurocomputational Explanations of Paranoia: From Cognition to Clinic" received the Wellcome Trust grant to apply neuroscience to...

    Brain and mental health illustrated

    Visual mismatch negativity identified as a mechanism of Parkinson's disease psychosis

    Reduced brain activity responding to unpredicted visual changes is a marker of psychosis in Parkinson’s disease and a potential therapeutic target

    iStock-925425712 EEG

    £1.45million awarded for EDEN Project, a trial exploring ketamine for depression with anorexia nervosa

    King’s researchers have been awarded the funds the MRC Developmental Pathway Funding Scheme to run a randomised controlled feasibility trial of oral ketamine...

    Someone talking to a professional

    Lord O'Shaughnessy visits King's College London and the NIHR King's Clinical Research Facility

    Lord O’Shaughnessy, Former Health Minister and Senior Partner at consultancy firm Newmarket Strategy visited IoPPN and the NIHR King's Clinical Research...

    Lord O’Shaughnessy with King's College academics

    Full house at 10th edition of IoPPN Research Festival

    The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) celebrated its 10th Research Festival in a packed Wolfson Lecture Theatre. This year's...

    RF graphic

    Structural brain differences found in people with Parkinson's Disease who experience psychosis

    New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has discovered structural brain differences in...

    The brain.

    Problems in thinking and attention linked to COVID-19 infection

    Evidence of cognitive deficits in people who have recovered from COVID-19 has been discovered in a new study of over 80,000 individuals.

    brain

    Events

    10Sep

    Pioneering Approaches in Experimental and Translational Medicine: A Two-Day Course

    This two-day course aims to inspire and prepare researchers embarking on careers in translational and experimental medicine.

    10Sep

    Pioneering Approaches in Experimental and Translational Medicine: A Two-Day Course 2026

    The course will feature inspiring talks, panel discussions with Q&As and networking opportunities.

    11May

    Resilience in Translational Research: Navigating Setbacks with Strength and Strategy

    This workshop explores how common challenges in translational research can be reframed as sources of learning, adaptability, and professional growth.

    Please note: this event has passed.

    24Feb

    Non-CTIMP Research Network Launch

    Join our launch event for talks and networking around demystifying regulatory approvals for experimental drug studies.

    Please note: this event has passed.

    Features

    IoPPN Research Culture Insights: Professor Mitul Mehta

    Mitul is Professor of Neuroimaging & Psychopharmacology at IoPPN and Director for the Centre for Innovative Therapeutics.

    Mitul Mehta RCBlog

    IoPPN Research Festival 2024 'Origins and new beginnings'

    The 2024 IoPPN Research Festival covered the theme ‘Origins and New Beginnings.’

    Rainbow Origami Cranes From Origin to End

      Research

      London landscape
      Ageing Research at King's (ARK)

      Cross faculty consortium addressing ageing and healthy longevity.

      pexels-anna-shvets-4226219-min
      ATTENS Project

      The ATTENS Project explores the potential of eTNS in improving symptoms, cognitive performance and the functioning of the brain in children with ADHD.

      Project status: Completed

      ebrain-cropped-780x440
      e-BRAIN

      e-BRAIN: The impact of early adversity on trajectories of brain maturation and mental health in young adolescents

      Project status: Ongoing

      MRI Scanner
      Identifying Neuroimaging Biomarkers of Bipolar Depression

      This study aims to identify brain scanning biomarkers which can be used to help diagnose and treat patients and the development of new medications.

      Project status: Completed

      Centre for Neuroimaging
      Ketamine Research

      Using brain imaging techniques, we will observe the effects of ketamine treatment on brain activity patterns and how this relates to any changes in the symptoms of treatment resistant depression.

      King’s Open Research Group Initiative (KORGI)

      The King’s Open Research Group Initiative (or KORGI) is an action-oriented committee composed of an interdisciplinary mix of senior academics and experienced research staff that seek to change policy and procedures to promote transparent, accessible and reproducible research.

      thumbnaillogogvs2
      Centre for Innovative Therapeutics (C-FIT)

      C-FIT accelerates research with the aim of transforming lives.

      CFIT_KCL_Thumbnails_LogoStacked_4_780_440ppi
      Point-of-care testing

      Point of care testing for clozapine levels in patient blood.

      Project status: Completed

      spilled-medication
      kEtamine for the treatment of DEpression with anorexia Nervosa (EDEN)

      The EDEN trial aims to investigate the effect of ketamine in alleviating depression with a diagnosis of persisting anorexia and treatment-resistant depression

      Project status: Ongoing

      News

      King's plays major role in £50 million government funded programme into mental health research

      Researchers at King's, University of Oxford and Cardiff University will help transform mental health data, clinical trials and industry partnerships as part...

      IoPPN signage

      Warm and consistent parenting can lead to meaningful changes in brain function and learning style in children with behaviour problems

      Parenting programmes can lead to changes in how children with conduct problems process rewards in their brains.

      Young children playing with adults

      Researchers receive £4.1million to research new modelling and treatment approaches for auditory hallucinations in people with psychosis

      The Wellcome Trust Mental Health Award will fund testing of a computational model of the role of cortical circuits in understanding auditory hallucinations...

      Abstract image of a brain from above

      £1.4 million awarded to study how brain experiences paranoia

      The project "Bridging the Neurocomputational Explanations of Paranoia: From Cognition to Clinic" received the Wellcome Trust grant to apply neuroscience to...

      Brain and mental health illustrated

      Visual mismatch negativity identified as a mechanism of Parkinson's disease psychosis

      Reduced brain activity responding to unpredicted visual changes is a marker of psychosis in Parkinson’s disease and a potential therapeutic target

      iStock-925425712 EEG

      £1.45million awarded for EDEN Project, a trial exploring ketamine for depression with anorexia nervosa

      King’s researchers have been awarded the funds the MRC Developmental Pathway Funding Scheme to run a randomised controlled feasibility trial of oral ketamine...

      Someone talking to a professional

      Lord O'Shaughnessy visits King's College London and the NIHR King's Clinical Research Facility

      Lord O’Shaughnessy, Former Health Minister and Senior Partner at consultancy firm Newmarket Strategy visited IoPPN and the NIHR King's Clinical Research...

      Lord O’Shaughnessy with King's College academics

      Full house at 10th edition of IoPPN Research Festival

      The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) celebrated its 10th Research Festival in a packed Wolfson Lecture Theatre. This year's...

      RF graphic

      Structural brain differences found in people with Parkinson's Disease who experience psychosis

      New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has discovered structural brain differences in...

      The brain.

      Problems in thinking and attention linked to COVID-19 infection

      Evidence of cognitive deficits in people who have recovered from COVID-19 has been discovered in a new study of over 80,000 individuals.

      brain

      Events

      10Sep

      Pioneering Approaches in Experimental and Translational Medicine: A Two-Day Course

      This two-day course aims to inspire and prepare researchers embarking on careers in translational and experimental medicine.

      10Sep

      Pioneering Approaches in Experimental and Translational Medicine: A Two-Day Course 2026

      The course will feature inspiring talks, panel discussions with Q&As and networking opportunities.

      11May

      Resilience in Translational Research: Navigating Setbacks with Strength and Strategy

      This workshop explores how common challenges in translational research can be reframed as sources of learning, adaptability, and professional growth.

      Please note: this event has passed.

      24Feb

      Non-CTIMP Research Network Launch

      Join our launch event for talks and networking around demystifying regulatory approvals for experimental drug studies.

      Please note: this event has passed.

      Features

      IoPPN Research Culture Insights: Professor Mitul Mehta

      Mitul is Professor of Neuroimaging & Psychopharmacology at IoPPN and Director for the Centre for Innovative Therapeutics.

      Mitul Mehta RCBlog

      IoPPN Research Festival 2024 'Origins and new beginnings'

      The 2024 IoPPN Research Festival covered the theme ‘Origins and New Beginnings.’

      Rainbow Origami Cranes From Origin to End